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Publications

  1. Mahuteau-Betzer F.
    Chimiothèque Nationale : Avancées et perspectives
    Médecine/Sciences, 2015, 31, 417-422
  2. Guillaume Kellermann, Markus Kaiser, Florent Dingli, Olivier Lahuna,Delphine Naud-Martin, Florence Mahuteau-Betzer, Damarys Loew,Evelyne S´egal-Bendirdjian, Marie-Paule Teulade-Fichou and Sophie Bombard
    Identification of human telomerase assembly inhibitors enabled by a novel method to produce hTERT
    Nucleic Acids Research, 2015, 1-12
  3. Lucas-Hourani M, Dauzonne D, Jorda P, Cousin G, Lupan A, Helynck O, Caignard G, Janvier G, André-Leroux G, Khiar S, Escriou N, Desprès P, Jacob Y, Munier-Lehmann H, Tangy F, Vidalain PO
    Inhibition of pyrimidine biosynthesis pathway suppresses viral growth through innate immunity
    PLoS Pathog. 2013;9(10):e1003678
  4. Prudent, R., Vassal-Stermann, E., Nguyen, C.H., Mollaret, M., Viallet, J., Castan, A., Barette, C., Pillet, C.,  Martinez, A., Soleilhac, E., Feige, J-J., Billaud, M., Florent J-C., and Lafanechère, L.
    Azaindole derivatives are inhibitors of microtubule dynamics, with anticancer and anti-angiogenic activities
    Br J Pharmacol. 2013, 168, 673-685
  5. Le Ly, TT., Vu, H.L., Naud-Martin, D., Bombled, M., Nguyen, C.H., and Molla A.
    New hydrosoluble benzo[e]pyridoindolones as potent inhibitors of aurora kinases.
    Chem. Med. Chem. 2013, 8, 289-296
  6. Ada Collura, Laetitia Marisa, Diletta Trojan, Olivier Buhard, Anaïs Lagrange, Arnaud Saget, Marianne Bombled, Patricia Méchighel, Mira Ayadi, Martine Muleris, Aurélien de Reynies, Magali Svrcek, Jean-Francois Fléjou, Jean-Claude Florent, Florence Mahuteau-Betzer, Anne-Marie Faussat, Alex Duval
    Extensive characterization of sphere models established from colorectal cancer cell lines
    Cell. Mol. Life Sci. 2013,117 (2), 316-323.
  7. Renaud Prudent, Emilie Vassal-Stermann, Chi-Hung Nguyen, Catherine Pillet, Anne Martinez, Chloé Prunier, Caroline Barette, Emmanuelle Soleilhac, Odile Filhol, Anne Beghin, Glaucio Valdameri, Stéphane Honoré, Samia Aci-Sèche, David Grierson, Juliana Antonipillai, Rong Li, Attilio Di Pietro, Charles Dumontet, Diane Braguer, Jean-Claude Florent, Stefan Knapp, Ora Bernard, Laurence Lafanechère
    Pharmacological Inhibition of LIM Kinase Stabilizes Microtubules and Inhibits Neoplastic Growth
    Cancer Research 2012, 72 (23), 4429-4449.
  8. Ceccaldi A, Rajavelu A, Champion C, Rampon C, Jurkowska R, Jankevicius G, Sénamaud-Beaufort C, Ponger L, Gagey N, Ali HD, Tost J, Vriz S, Ros S, Dauzonne D, Jeltsch A,  Guianvarc'h D, Arimondo PB.
    C5-DNA methyltransferase inhibitors: from screening to effects on zebrafish embryo development
    ChemBioChem. 2011, 12,1337-45
  9. López-Ramos M, Prudent R, Moucadel V, Sautel CF, Barette C, Lafanechère L, Mouawad L, Grierson D, Schmidt F, Florent JC, Filippakopoulos P, Bullock AN, Knapp S, Reiser JB and Cochet C
    New potent dual inhibitors of CK2 and Pim kinases: Discovery and structural insights.
    FASEB Journal 2010, 24 (9), 3171-3185.
  10. Thérèse David-Pfeuty, Michel Legraverend, Odile Ludwig, David S. Grierson
    Targeting the cell cycle and the PI3K pathway: A possible universal strategy to reactivate innate tumor suppressor programmes in cancer cells
    International Journal of Oncology, 2010, 36, 873-881
  11. Prudent, R.;  Moucadel, V.; Nguyen, C.H; Barette, C.; Schmidt, F.; Florent, J.-C.; Lafanechere, L.; Sautel, C. F.; Duchemin-Pelletier, E.; Spreux, E.; Filhol, O.; Reiser, J.-B.; Cochet, C.
    Antitumor activity of pyridocarbazole and benzopyridoindole derivatives that inhibit protein kinase CK2
    Cancer Research 2010, 70 (23), 9865-9874.
  12. T.M. Hoang, B. Favier, A. Valette, C. Barette, C.H. Nguyen, L. Lafanechere, D.S. Grierson, S. Dimitrov , A. Molla
    Benzo [e]pyridoindoles, novel inhibitors of the aurora kinases
    Cell Cycle 2009, 8 (5), 765-772
  13. Keriel, F. Mahuteau-Betzer, C. Jacquet, M. Plays, D. Grierson, M. Sitbon, J. Tazi
    Protection against Retrovirus Pathogenesis by SR Protein Inhibitors
    PLoS One 2009, 2, 4, e4533
  14. R. Prudent, M. Lopez-ramos, V. Moucadel, C. Barette, D. Grierson, L. Mouawad, J.-C. Florent, L. Lafanechere, F. Schmidt, C. Cochet
    Salicylaldehyde Derivatives as New Protein Kinase CK2 Inhibitors
    Biochim. Biophys Acta 2008, 1780, 1412-1420
  15. R. Prudent, V. Moucadel, M. Lopez Ramos, S. Aci, B. Laudet, L. Mouawad, C. Barette, J. Einhorn, C. Einhorn, J.-N. Denis, G. Bisson, F. Schmidt, S. Roy, L. Lafanechere, J.-C. Florent, C. Cochet
    Expanding the chemical diversity of CK2 inhibitors
    Mol Cell Biochem 2008, 316, 71-85
  16. N. Bakkour, YL. Lin, S. Maire, L. Ayadi, F. Mahuteau-Betzer, CH. Nguyen, C. Mettling, P. Portales, D.S. Grierson, B. Chabot, P. Jeanteur, C. Branlant, P. Corbeau, J. Tazi
    Small-molecule inhibition of HIV pre-mRNA splicing as a novel antiretroviral therapy to overcome drug resistance
    PLoS Pathogens 2007, 3 (10), 1530-1539
  17. S. Durand, N. Cougot, F. Mahuteau-Betzer, C.H. Nguyen, D.S. Grierson, E. Bertrand, J. Tazi, F. Lejeune
    Inhibition of nonsense-mediated mRNA decay (NMD) by a new chemical molecules reveals the dynamic of NMD factors in P-bodies
    J. Cell Biol. 2007, 178(7), 1145-1160
  18. Erve, Y. Saoudi, C. Guetta, S. Thirot, C.H. Nguyen, D.S. Grierson, A.V. Popov
    BENA435, A New Cell-Permiable Photoactivated Green Fluorescent DNA Dye
    Nucleic Acids Res. 2006, 34 (5), e43
  19. J. Soret, N. Bakkour, S. Maire, S. Durand, L. Zekri, M. Gabut, W. Fic, G. Divita, C. Rivalle, D. Dauzonne, C.H. Nguyen, P. Jeanteur, J. Tazi
    Selective modification of alternative splicing by indole derivatives that target serine-arginine-rich protein splicing factors
    Proc. Natl. Acad. Sci. USA 2005, 102, 8764-8769